Variation in background intensity affects PET-based gross tumor volume delineation in non-small-cell lung cancer: the need for individualized information

G Chen, Z Yao, X Fan, Y Zhang, H Gao, W Qian… - Radiotherapy and …, 2013 - Elsevier
Purpose Efficient tumor volume delineation by the combined use of PET/CT scanning is
necessary for the proper treatment of non-small cell lung cancer (NSCLC). To understand
the effect of variation in background intensity on PET-based gross tumor volume (GTV)
delineation, we determined the background standard uptake values (SUVs) in normal lung,
aorta (blood pool), and liver tissues and determined GTVs using different methods. Methods
Thirty-seven previously untreated patients with pathologically confirmed NSCLC underwent …
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